(REUTERS)
A medevac plane crashed in Philadelphia on Friday with a child and five others on board, the air ambulance company that operated it said, adding that it had not confirmed any survivors.
Jet Rescue Air Ambulance said its aircraft crashed with four crew members, one paediatric medical patient and the patient's escort on board.
The company said in a statement, "At this time, we cannot confirm any survivors."
State and local officials said late on Friday they could not yet confirm how many people may have died on the ground after the plane slammed into a heavily populated portion of the city.
Pennsylvania Governor Josh Shapiro told a press conference at the crash scene that "we know there will be loss in this region."
"We want to offer our thoughts and serious prayers for those grieving now," Shapiro said.
President Donald Trump wrote on social media that it was "so sad to see the plane go down in Philadelphia, Pennsylvania. More innocent souls were lost. Our people are engaged. First Responders are already being given credit for doing a great job."
The crash follows this week's collision of an American Airlines jet and a U.S. Army Black Hawk helicopter over Washington, D.C., which killed 67 in the deadliest aeroplane crash in the U.S. since 2009.
The U.S. Federal Aviation Administration said six people were on the Learjet 55 that crashed around 6:30 p.m. (0030 GMT) on Friday. Local media reported it was near the Roosevelt Mall in northeast Philadelphia and that there were multiple injuries on the ground.
Video aired on local TV stations showed the plane in a sharp dive before hitting the ground and exploding in a massive fireball.
Philadelphia Mayor Cherelle Parker told a press conference at the scene that several houses and cars had been engulfed in flames. She said the situation is "all hands on deck; that's where we are right now."
Officials said it was not clear what caused the crash. The weather was cold and rainy, and there was low visibility when the plane went down.
The FAA said the air ambulance had left Northeast Philadelphia Airport and was headed to Springfield-Branson National Airport in Missouri, about 1,800 km to the southwest.
Images broadcast by the Philadelphia CBS affiliate showed a large fire and several fire trucks at the crash scene. According to TV images, the fires were mostly out about two hours after the crash.
Neither the Philadelphia police nor the fire department immediately responded to requests for comment.