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World Health Organisation prequalifies new oral simplified vaccine for cholera

World Health Organisation prequalifies new oral simplified vaccine for cholera
20 Apr 2024 16:34


A new oral vaccine for cholera received prequalification by the World Health Organisation (WHO).

The inactivated oral vaccine Euvichol-S has a similar efficacy to existing vaccines but a simplified formulation, allowing opportunities to rapidly increase production capacity.

Director of the WHO Department for Regulation and Prequalification, Dr Rogerio Gaspar, commented,“The new vaccine is the third product of the same family of vaccines we have for cholera in our WHO prequalification list.” 

“The new prequalification is hoped to enable a rapid increase in production and supply which many communities battling with cholera outbreaks urgently need,” he explained.

WHO prequalification list already includes Euvichol and Euvichol-Plus inactivated oral cholera vaccines produced by EuBiologicals Co., Ltd, Republic of Korea, which also produces the new vaccine Euvichol-S.

Notably, vaccines provide the fastest intervention to prevent, limit and control cholera outbreaks, but supplies have been at the lowest point amidst countries facing dire shortcomings in other areas of cholera prevention and management such as safe water, hygiene and sanitation.

It is also worth noting that there were 473,000 cholera cases reported to WHO in 2022 -- double the number from 2021. Further increase of cases by 700,000 was estimated for 2023.

A total of 23 countries are currently reporting cholera outbreaks with most severe impacts seen in the Comoros, Democratic Republic of the Congo, Ethiopia, Mozambique, Somalia, Zambia, and Zimbabwe.

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